Pharmacogenomics research themes
PGNI is advancing pharmacogenomics research, including AI methods, to support individualized treatment.
PGNI's research agenda is organized around themes rather than individual studies.
What PGNI's research is organized around
01. Applied precision medicine & clinical implementation
How genetic variation shapes individual drug response, and how that evidence moves into real prescribing workflows — test ordering, interpretation, point-of-care decision support, and validation of dose-prediction models.
02. Artificial intelligence in pharmacogenomics
Applying computational and machine learning methods to pharmacogenomic data, including the consent and governance questions that use raises.
03. Green Pharmacogenomics & Sustainable Medicines
Using pharmacogenomic evidence to reduce medication waste and the environmental footprint of prescribing.
04. Health equity & underserved populations
Identifying and addressing the structural, economic, and geographic barriers that determine who benefits from precision prescribing, with research designed for underserved and underrepresented communities.
05. Nutrigenomics & Epigenomics
How nutrients, herbal products, and epigenetic regulation interact with genetic variation to shape drug response.
06. Pharmacovigilance & drug safety
Using pharmacogenomic evidence to anticipate and reduce adverse drug reactions and to make prescribing safer.
07. Population pharmacogenomics & genomic diversity
Characterizing genetic variation across populations, with attention to groups underrepresented in existing pharmacogenomic reference data and clinical guidance.
08. Research ethics & regulatory science
The ethical infrastructure and regulatory pathways — informed consent, data governance, IRB review, FDA and international frameworks — that pharmacogenomic research depends on.
09. Toxicogenomics
Understanding how genetic variation shapes individual susceptibility to drug toxicity.
PGNI welcomes research collaboration and externally funded research
PGNI develops research programs around the themes above and works with partners who share its focus on pharmacogenomics and equitable access. Investigators, institutions, sponsors, and funders are invited to collaborate.
From training to real research
PGNI's courses and fellowship program take participants from learning pharmacogenomics to carrying out a real research project, from question to results. PGNI alumni can go on to become Affiliated Researchers with ongoing access to PGNI's IRB.
Where to start with PGNI
Answer one question and we'll point you to the right next step.
Have your research reviewed by PGNI's IRB
Independent or practice-based researchers with their own pharmacogenomics-related research project can submit it to PGNI's IRB for independent, pharmacogenomics-specialized ethical and regulatory review, without needing to join PGNI as an Affiliated Researcher.
Apply for ReviewStart with Intro to Pharmacogenomics
New to pharmacogenomics research or don't yet have a project of your own? Begin with PGNI's Intro to Pharmacogenomics, continue to IRB & Ethics, and finish with the Pharmacogenomics Research Methods course, where you complete a real research project from question to results. Graduates can go on to become Affiliated Researchers with ongoing access to PGNI's IRB. Experienced researchers can instead apply to the PGNI Pharmacogenomics Research Fellowship Program.
Explore the courses Explore the fellowship programWorking on one of these themes already? Contact PGNI.